In-Vitro Activity of Teicoplanin against Clinical MethicillinResistant Staphylococcus aureus Isolates. J Microbiol Biotechnol, 2017, 2(1): 000112
نویسنده
چکیده
Aim: To evaluate the in vitro activity of teicoplanin against clinical methicillin resistant Staphylococcus aureus isolates was the aim of this study Methods and Material: A total of 62 previously confirmed MRSA isolates were included in this study. Susceptibility testing and result interpretation of isolates to teicoplanin was performed by the E test and disk diffusion method as per Clinical and Laboratory Standards Institute (CLSI) M100-S25 recommendations. Results: Teicoplanin appears to exhibit excellent in vitro activity against the MRSA isolates. Conclusion: The high in vitro susceptibility to teicoplanin in this population and fewer adverse drug effects, teicoplanin may be considered a useful first line antibiotic agent in the treatment of infections caused by MRSA.
منابع مشابه
Cephalosporin-Glycopeptide Combinations for Use against Clinical Methicillin-Resistant Staphylococcus aureus Isolates: Enhanced In vitro Antibacterial Activity
The empirical combination of both a beta-lactam and glycopeptide to counter potential staphylococcal pathogens may improve the clinical outcomes for cases of Staphylococcus aureus bacteremia. We reported comparative in vitro studies of combination effects of different cephalosporins (i.e., cefazolin, cefmetazole, cefotaxime, and cefepime) combined with glycopeptides for 34 randomly selected met...
متن کاملIn-vitro bactericidal activity of cefpirome and cefamandole in combination with glycopeptides against methicillin-resistant Staphylococcus aureus.
The bactericidal activity in vitro of cefpirome plus either vancomycin or teicoplanin was compared with that of a cefamandole-vancomycin combination against ten clinical isolates of homogeneous methicillin-resistant Staphylococcus aureus. Cefpirome (0.125 x MIC) combined with vancomycin (0.5-2 x MIC) or teicoplanin (0.5-4 x MIC) acted synergically against the ten isolates. Similar effects were ...
متن کامل[In vitro activity of linezolid against clinical isolates of methicillin-resistant Staphylococcus aureus].
In recent years, there has been a dramatic increase in the number of infections caused by multidrug-resistant Gram-positive microorganisms, making necessary the search for alternative antibacterial agents. Linezolid is a new synthetic antimicrobial agent with activity against multidrug-resistant Gram-positive cocci. The objective of this study was to determine the in vitro activity of linezolid...
متن کاملIn-vitro activity of ramoplanin (a novel lipoglycopeptide), vancomycin, and teicoplanin against gram-positive clinical isolates from cancer patients.
The in-vitro activities of ramoplanin, vancomycin, and teicoplanin against Gram-positive organisms isolated from cancer patients were determined. Ramoplanin was the most active agent tested inhibiting all isolates at a concentration of < or = 0.5 mg/L. Although all isolates were also susceptible to vancomycin and teicoplanin, their activities were surpassed by that of ramoplanin. The activity o...
متن کاملSuspected Horse-to-Human Transmission of MRSA ST398
1. Pu S, Han F, Ge B. Isolation and characterization of methicillin-resistant Staphylococcus aureus strains from Louisiana retail meats. Appl Environ Microbiol. 2009;75:265–7. doi:10.1128/AEM.0111008 2. Weese JS, Avery BP, Reid-Smith RJ. Detection and quantifi cation of methicillinresistant Staphylococcus aureus (MRSA) clones in retail meat products. Lett Appl Microbiol. 2010;51:338–42. doi:10....
متن کامل